Can physics principles help explain why non-tuberculous mycobacterial lung disease is more severe in the right middle lobe and lingula?

Resection of the right middle lobe and lingula in children for middle lobe/lingula syndrome.

STUDY OBJECTIVE To review our experience with specific characteristics, indications, and results of pulmonary resection in children with middle lobe/lingula syndrome. DESIGN Retrospective cohort study. SETTING Thoracic Surgery Department, Chest Diseases Hospital, Kuwait. PATIENTS AND INTERVENTION Thirteen children with middle lobe, lingula, or both syndromes were treated with pulmonary re...

Isolated disease of the middle lobe and lingula.

Non-tuberculous mycobacterial disease & aspergillus- related lung disease in bronchiectasis

Objective: To determine if patients with bronchiectasis and non-tuberculous mycobacteria (NTM) have a higher prevalence of aspergillus-related lung disease. Methods: A series of 30 consecutive patients with bronchiectasis and NTM (cases) were compared with 61 patients with bronchiectasis and no evidence of NTM (controls). Aspergillus serology and computerised tomography (CT) of thorax were used...

Monocyte-derived macrophages do not explain susceptibility to pulmonary non-tuberculous mycobacterial disease

Pulmonary infections with non-tuberculous mycobacteria (NTM) affect a subset of older individuals (mostly women) with no known immunological defects. As NTMs are intracellular pathogens, it is important to establish whether NTM disease is associated with defective production of Th1 cytokines or poor responses by host macrophage/monocytes. We have shown that patients display vigorous production ...

Non-tuberculous mycobacterial lymphadenitis.

Most cases of mycobacterial lymphadenitis in children are caused by non-tuberculous mycobacteria, previously called the atypical mycobacteria. It is important to differentiate non-tuberculous mycobacterial lymphadenitis from tuberculous lymphadenitis as the treatment is different. We reviewed 19 children (12 girls and seven boys) with non-tuberculous mycobacterial lymphadenitis to define likely...